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Document ID (ISN)75186
CIS number 00-1068
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Shih T.S., Liou S.H., Chen C.Y., Chou J.S.
Title Correlation between urinary 2-methoxy acetic acid and exposure to 2-methoxy ethanol
Bibliographic information Oct. 1999, Vol.56, No.10, p.674-678. Illus. 21 ref.
Abstract To examine the correlation between airborne 2-methoxy ethanol (ME) exposures and urinary 2-methoxy acetic acid (MAA), 8-hour time weighted average (TWA) personal breathing zone samples and urine samples before and after the shift were collected from Monday to Saturday for 27 workers exposed to ME and on Friday for 30 control workers. No correlation was found between airborne exposure to ME and urinary MAA for special operation workers due to the use of personal protective equipment. For regular operation workers, a significant correlation was found between urinary MAA (mg/g creatinine) on Friday at the end of the shift and the weekly mean exposures of ME in a 5 day working week. The proposed biological exposure index BEI, which corresponds to exposure for 5 days and 8 hours a day to 5ppm, extrapolated from the regression equation, is 40mg MAA/g creatinine. A significant correlation was also found between the weekly increase of urinary MAA and the weekly mean exposures of ME. The recommended value of the weekly increase of urinary MAA for 5 days repeated exposures of 5ppm ME is 20mg/g creatinine.
Descriptors (primary) methoxyacetic acid; methoxyethanol; determination in urine; exposure tests; electronics industry
Descriptors (secondary) personal sampling; exposure evaluation; comparative study; dose-response relationship; determination in air; personal protective equipment
Document type D - Periodical articles
Country / State or ProvinceTaiwan (China)
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Biological monitoring
Glycol ethers
Electronics industry
Manufacturing of electrical appliances and equipment