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Document ID (ISN)75126
CIS number 00-1062
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Kim Y., Lee N.R., Sakai T., Kim K.S., Yang J.S., Park S., Lee C.R., Cheong H.K., Moon Y.
Title Evaluation of exposure to ethylene glycol monoethyl ether acetates and their possible haematological effects on shipyard painters
Bibliographic information June 1999, Vol.56, No.6, p.378-382. 19 ref.
Abstract The aim of this study was to evaluate exposure to mixed solvents containing ethylene glycol monoethyl ether acetate (EGEEA) in shipyard painters in order to determine if EGEEA is toxic to the bone marrow. The mean exposure concentration to EGEEA in the high and low exposure groups were 3.03ppm and 1.76ppm, respectively. The concentrations of methyl hippuric acid and ethoxyacetic acid in the high exposure group were significantly higher than those in the control group. The mean white blood cell counts in the high exposure group were significantly lower than in the control group, and a significant proportion, six of the 57 painters, were leucopenic; none of the controls were affected. The high rate of possible haematological effects among shipyard painters and a hygienic evaluation of their working environment in the present study suggests that EGEEA might be toxic to bone marrow.
Descriptors (primary) acetates; alkoxyethanols; haematological effects; shipyards; organic solvents; painting
Descriptors (secondary) ethoxyethanol; blood count; 2-ethoxyacetic acid; methoxyethanol; determination in urine; 2-methoxyethyl acetate; bone marrow diseases; leukopenia; exposure evaluation; 2-ethoxyethyl acetate
Document type D - Periodical articles
Country / State or ProvinceJapan; Korea, Republic of
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Blood diseases
Surface treatment
Glycol ethers
Esters and salts
Shipbuliding and ship repair