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Document ID (ISN)75056
CIS number 00-742
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1998
Convention or series no.
Author(s) Garcia A.M., Fletcher T.
Title Maternal occupation in the leather industry and selected congenital malformations
Bibliographic information Apr. 1998, Vol.55, No.4, p.284-286. 8 ref.
Abstract Cases and controls were selected from eight public hospitals in Spain. Cases were located from the hospital discharge records, including children born and diagnosed in some of the selected hospitals during their first year of life. Controls were selected from births without congenital defects in the same hospitals and dates of the cases. Both parents of selected children were interviewed (mainly by phone) and information about potential confounding variables and occupational history during the three years before the birth was collected in structured questionnaires. A total of 261 cases and the same number of controls were included in the study. Adjusted odds ratios (ORB) were estimated for maternal occupation in the leather industry in the period between three months before the conception and the birth of the child, and each selected group of congenital malformations: nervous system defects, cardiac defects of closure, oral clefts, epispadia or hypospaslia, and multiple anomalies. These data are compatible with an increased risk for oral clefts in the offspring of women working in the leather industry.
Descriptors (primary) genetic abnormalities; leather and fur industries; expectant mothers; genetic effects
Descriptors (secondary) lip diseases; ureter diseases; solvents; nervous system; questionnaire survey; case-control study; heart diseases
Document type D - Periodical articles
Country / State or ProvinceSpain; United Kingdom
Subject(s) Leather, fur and footwear
Broad subject area(s) Industries and occupations
Browse category(ies) Antifertility and prenatal effects
Footwear, leather and fur industry
Genetic factors in reaction to exposures