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Document ID (ISN)75012
CIS number 00-789
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Bianchi C., Brollo A., Ramani L., Zuch C.
Title Asbestos exposure in lung carcinoma: A necropsy-based study of 414 cases
Bibliographic information Sep. 1999, Vol.36, No.3, p.360-364. 22 ref.
Abstract Occupational history, pleural plaques and lung asbestos bodies were investigated in 414 consecutive cases of lung carcinoma examined at necropsy at the Hospital of Monfalcone, Italy. The series included 353 men and 61 women, aged 38-97 years. The male patients had worked in industry in 74% of cases (60% in shipbuilding). Men showed pleural plaques in 82% of cases. Asbestos bodies were observed in routine lung sections in 34.8%, and in 31% exceeded the value of 5,000 bodies per gramme of dried tissue. Among women the principal features were: history or domestic exposure to asbestos in 36% of the cases, prevalence of pleural plaques 34% (moderate or large plaques 15%), asbestos bodies in routine lung sections in 3.3% and there was no case with an asbestos body burden over 5,000/g. The fraction of asbestos-related carcinomas among male patients varied between 24.7 and 61%, depending on the criteria used for attribution. Different criteria indicated that about 60% of the present lung carcinomas among men as plausibly attributable to asbestos.
Descriptors (primary) asbestos; autopsy; lung cancer
Descriptors (secondary) pleural thickening; Italy; pulmonary fibrosis; asbestos bodies; job-exposure relation; shipbuilding industry; women; sex-linked differences; survey
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Asbestos
Diseases of the respiratory system (except for pneumoconiosis & similar)