|Document ID (ISN)||74993|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Rapiti E., Sperati A., Miceli M., Forastiere F., Di Lallo D., Cavariani F., Goldsmith D.F., Perucci C.A.
||End stage renal disease among ceramic workers exposed to silica
||Aug. 1999, Vol.56, No.8, p.559-561. 28 ref.
||To evaluate whether ceramic workers exposed to silica experience an excess of end stage renal disease, a cohort of 2,980 male ceramic workers was enrolled during the period 1974-91 in Civitacastellana, Lazio, Italy. For each worker, employment history, smoking data and X-ray film readings were available. Vital status was ascertained for all cohort members. All 2,820 people still alive and resident in the Lazio region as of June 1994 were searched for a match in the regional end stage renal diseases registry, which records all patients undergoing dialysis treatment in public and private facilities of the region. A total of 6 cases was detected when 1.87 were expected. The excess risk was present among non-smokers and smokers, as well as among workers without silicosis and workers with silicoses. The risk was higher among subjects with <20 years since first employment than among those employed >20 years. These results provide further evidence that exposure to silica dust among ceramic workers is associated with nephrotoxic effects.
||silica; pottery industry; renal diseases; morbidity
||Italy; quartz; smoking; silicosis; radiography; long-term exposure; health service records; statistical evaluation; cohort study
||D - Periodical articles
|Country / State or Province||Italy; USA|
|Broad subject area(s)
||Industries and occupations
||Diseases of the kidney and the urinary system
Glass, pottery and related materials