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CISDOC database

Document ID (ISN)74971
CIS number 00-783
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1999
Convention or series no.
Author(s) Tan E., Leow Y.H., Ng S.K., Goh C.L.
Title A study of sensitization rate to sesquiterpene lactone mix in Singapore
Bibliographic information Aug. 1999, Vol.41, No.2, p.80-83. 13 ref.
Abstract This is a report on a study of the sensitization rate to sesquiterpene lactone (SL) mix performed at the National Skin Centre, Singapore. In a retrospective review of 1,256 patients who were patch tested to SL mix (0.1%) from January 1995 to December 1997, 18 out of 1,256 patients reacted positively to SL mix. Their ages ranged from 13 to 58 years. There was a female preponderance, with a female: male ratio of 3.5:1. The most common clinical presentations were dermatitis of the hands or face or generalized dermatitis. After extensive evaluation, only 2 patients had a positive patch test reaction that was of current clinical relevance. 13 patients had concomitant sensitization to other allergens. The three commonest concomitant allergens were nickel, balsam of Peru and fragrance mix. In the series, SL allergy was more common in females and the mean age was lower compared to the classical Compositae dermatitis. The sensitization rate was comparable to other studies, although the clinical relevance was only 11%.
Descriptors (primary) plants; sesquiterpenes; dermatitis; skin allergies
Descriptors (secondary) sensitization dermatitis; Singapore; case study; medicinal plants; frequency rates; long-term study; skin tests; sex-linked differences; eczema
Document type D - Periodical articles
Country / State or ProvinceSingapore
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Aliphatic and alicyclic hydrocarbons