|Document ID (ISN)||74904|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Vanhanen M., Tuomi T., Tiikkainen U., Tupasela O., Voutilainen R., Nordman H.
||Risk of enzyme allergy in the detergent industry
||Feb. 2000, Vol.57, No.2, p.121-125. 24 ref.
||To assess the prevalence of enzyme sensitization in a detergent factory, 40 workers in manufacturing, packing and maintenance, and 36 non-exposed persons in the management and sales departments were subjected to skin prick and radioallergosorbent tests. Nine workers were sensitized to enzymes in the exposed group of 40, whereas none were sensitised in the non-exposed group. All the sensitized workers had symptoms at work; all had rhinitis and one had asthma. Airborne protease concentrations were generally <20ng/m3, but occasional peak values up to 80ng/m3 were detected in the packing and maintenance tasks, and high values of >1µg/m3 in the mixing area. Despite the use of encapsulated enzyme preparations, high enzyme concentrations in workplace air are possible, resulting in a higher risk of sensitization than expected.
||enzymes; skin allergies; sensitization; allergic respiratory disorders; detergent industry
||airborne dust; rhinitis; proteases; determination in air; questionnaire survey; cross-sectional study; skin tests; allergic asthma
||D - Periodical articles
|Country / State or Province||Finland|
||Chemicals, plastics and rubber
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)