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Document ID (ISN)74904
CIS number 00-803
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Vanhanen M., Tuomi T., Tiikkainen U., Tupasela O., Voutilainen R., Nordman H.
Title Risk of enzyme allergy in the detergent industry
Bibliographic information Feb. 2000, Vol.57, No.2, p.121-125. 24 ref.
Abstract To assess the prevalence of enzyme sensitization in a detergent factory, 40 workers in manufacturing, packing and maintenance, and 36 non-exposed persons in the management and sales departments were subjected to skin prick and radioallergosorbent tests. Nine workers were sensitized to enzymes in the exposed group of 40, whereas none were sensitised in the non-exposed group. All the sensitized workers had symptoms at work; all had rhinitis and one had asthma. Airborne protease concentrations were generally <20ng/m3, but occasional peak values up to 80ng/m3 were detected in the packing and maintenance tasks, and high values of >1µg/m3 in the mixing area. Despite the use of encapsulated enzyme preparations, high enzyme concentrations in workplace air are possible, resulting in a higher risk of sensitization than expected.
Descriptors (primary) enzymes; skin allergies; sensitization; allergic respiratory disorders; detergent industry
Descriptors (secondary) airborne dust; rhinitis; proteases; determination in air; questionnaire survey; cross-sectional study; skin tests; allergic asthma
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Chemical industry
Skin diseases