|Document ID (ISN)||74823|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Elevated risk for male breast cancer after occupational exposure to gasoline and vehicular combustion products
||Apr. 2000, Vol.37, No.4, p.349-352. 25 ref.
||Automotive gasoline contains benzene, 1,3-butadiène, 1,2-dibromoethane and 1,2-dichloroethane, and the combustion products include certain polycyclic aromatic hydrocarbons, all of which have shown mammary gland carcinogenicity in long-term bioassays. A case control study on male breast cancer morbidity was established among members of a pension fund. Employment histories were reconstructed for each of 230 cases and 12,880 control subjects based on computerized records. When a lag time of at least 10 years was taken into account, the odds ratio for breast cancer among men with over three months of employment in occupations with potential exposure to gasoline and combustion products was 2.5. Among men younger than 40 years at the time of first employment, the odds ratio was 5.4. This study supports the hypothesis that occupational exposure to gasoline vapours and combustion products may play a role in the causation of male breast cancer.
||motor fuel; polycyclic hydrocarbons; breast cancer
||1,2-dichloroethane; benzene; butadiene; hazard evaluation; frequency rates; age-linked differences; statistical evaluation; dibromoethane; case-control study
||D - Periodical articles
|Country / State or Province||Denmark|
||Toxic and dangerous substances
|Broad subject area(s)
||Occupational medicine, epidemiology