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CISDOC database

Document ID (ISN)74685
CIS number 00-472
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Hirsch A.R., Zavala G.
Title Long term effects on the olfactory system of exposure to hydrogen sulphide
Bibliographic information Apr. 1999, Vol.56, No.4, p.284-287. 15 ref.
Abstract Chronic effects of hydrogen sulfide (H2S) on cranial nerve I (nervi olfactorii) have been only minimally described. In this study, chemosensations (smell and taste) were evaluated in eight men who complained of continuing dysfunction 2-3 years after the start of occupational exposure to H2S. Various bilateral (both nostrils) and unilateral (one nostril at a time) odour threshold tests with standard odorants as well as the Chicago smell test, a three-odour detection and identification test and the University of Pennsylvania smell identification test, and a series of 40 scratch and sniff odour identification tests were administered. Six of the eight patients showed deficits of various degrees. Two had normal scores on objective tests, but thought that they continued to have problems. H2S apparently can cause continuing, sometimes unrecognized olfactory deficits. Further exploration into the extent of such problems among workers exposed to H2S is warranted.
Descriptors (primary) loss of smell; hydrogen sulfide
Descriptors (secondary) long-term exposure; odour threshold
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of other sense organs (other than the eye and the ears)
Inorganic sulfur compounds
Inorganic substances