| Document ID (ISN) | 74660 |
| CIS number |
00-479 |
| ISSN - Serial title |
1351-0711 - Occupational and Environmental Medicine |
| Year |
2000 |
| Convention or series no. |
|
| Author(s) |
Ohayo-Mitoko G.J.A., Kromhout H., Simwa J.M., Boleij J.S.M., Heederik D. |
| Title |
Self reported symptoms and inhibition of acetylcholinesterase activity among Kenyan agricultural workers |
| Bibliographic information |
Mar. 2000, Vol.57, No.3, p.195-200. 33 ref. |
| Abstract |
The objective was to assess health hazards posed by pesticides on agricultural workers in Africa. Complete data were available for 256 exposed subjects and 152 controls from four regions in Kenya, who were given a structured questionnaire. Prevalence ratios were estimated for symptoms with changes in cholinesterase activity in serum. A significant change in symptom prevalence was found in the controls with a higher prevalence in the low-exposure period. Analysis of the relation between cholinesterase inhibition and symptoms showed that prevalence ratios were significantly >1 for respiratory, eye and central nervous system symptoms for workers with >30% inhibition. The results suggest a relation between exposure and acetylcholinesterase inhibition, acetylcholinesterase activity, and respiratory, eye, and central nervous system symptoms. |
| Descriptors (primary) |
acetylcholinesterase; agriculture; symptoms; pesticides |
| Descriptors (secondary) |
Kenya; frequency rates; questionnaire survey; exposure evaluation |
| Document type |
D - Periodical articles |
| Country / State or Province | Kenya; Netherlands |
| Subject(s) |
Agriculture, fishing, animal husbandry
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Agriculture
Agricultural chemicals
|
