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CISDOC database

Document ID (ISN)74660
CIS number 00-479
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Ohayo-Mitoko G.J.A., Kromhout H., Simwa J.M., Boleij J.S.M., Heederik D.
Title Self reported symptoms and inhibition of acetylcholinesterase activity among Kenyan agricultural workers
Bibliographic information Mar. 2000, Vol.57, No.3, p.195-200. 33 ref.
Abstract The objective was to assess health hazards posed by pesticides on agricultural workers in Africa. Complete data were available for 256 exposed subjects and 152 controls from four regions in Kenya, who were given a structured questionnaire. Prevalence ratios were estimated for symptoms with changes in cholinesterase activity in serum. A significant change in symptom prevalence was found in the controls with a higher prevalence in the low-exposure period. Analysis of the relation between cholinesterase inhibition and symptoms showed that prevalence ratios were significantly >1 for respiratory, eye and central nervous system symptoms for workers with >30% inhibition. The results suggest a relation between exposure and acetylcholinesterase inhibition, acetylcholinesterase activity, and respiratory, eye, and central nervous system symptoms.
Descriptors (primary) acetylcholinesterase; agriculture; symptoms; pesticides
Descriptors (secondary) Kenya; frequency rates; questionnaire survey; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceKenya; Netherlands
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s) Chemical safety
Browse category(ies) Agriculture
Agricultural chemicals