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Document ID (ISN)74656
CIS number 00-470
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 2000
Convention or series no.
Author(s) Viaene M.K., Masschelein R., Leenders J., De Groof M., Swerts L.J.V.C., Roels H.A.
Title Neurobehavioural effects of occupational exposure to cadmium: A cross sectional epidemiological study
Bibliographic information Jan. 2000, Vol.57, No.1, p.19-27. Illus. 62 ref.
Abstract The aim of this cross-sectional study of 89 adult men (42 exposed to Cd and 47 control workers) was to investigate the toxic potential of chronic occupational exposure to cadmium (Cd) on neurobehavioural functions. Subjects were given a computer assisted neurobehavioural test, a validated questionnaire to assess neurotoxic complaints and a self-administered questionnaire to detect neuropathy and dysfunction of the autonomic nervous system. Historical and current data on biomonitoring of exposure to Cd and on microproteinuria were also available. Results show that the slowing of visuomotor functioning on neurobehavioural testing and increase in complaints consistent with peripheral neuropathy, complaints about equilibrium, and complaints about concentration ability were dose dependently associated with urinary Cd.
Descriptors (primary) neurotoxic effects; cadmium; toxic substances
Descriptors (secondary) nervous function tests; epidemiologic study; determination in urine; dose-response relationship; cross-sectional study
Document type D - Periodical articles
Country / State or ProvinceBelgium
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Cadmium and compounds
Inorganic substances