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Document ID (ISN)74365
CIS number 00-258
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1999
Convention or series no.
Author(s) Murata K., Yano E., Shinozaki T.
Title Impact of shift work on cardiovascular functions in a 10-year follow-up study
Bibliographic information June 1999, Vol.25, No.3, p.272-277. 33 ref.
Abstract Electorcardiography and blood pressure of 158 shift workers and 75 day workers at a copper smelter were followed for ten years in order to determine if shift work affects cardiovascular function. In 1986 and 1996, the adjusted QT interval (QTc) was significantly longer in shift workers than in day workers. Of workers with a normal QTc in 1986, 15% had developed a prolonged QTc in 1996. Among the workers with a normal QTc in 1986, shift workers had a significantlylonger QTc than did day workers when the QTc was examined in 1996. In addition, day-shift work in the group with a normal QTc was significantly related to the QTc in 1996 after control for age, work duration, biochemical indicators, smoking and drinking habits. However, the blood pressures of the shift and day workers did not differ significantly, and in 1996 the values of both groups were significantly elevated. The data suggest that shift work is associated with QTc prolongation and may explain the increased risk for cardiovascular diseases due to shift work.
Descriptors (primary) cardiovascular diseases; shift work
Descriptors (secondary) alcoholism; smoking; electrocardiography; long-term study; cardiovascular function tests; blood pressure
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Occupational pathology
Broad subject area(s) Physiology, ergonomics
Browse category(ies) Alcohol and drug abuse
Cardiovascular diseases