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Document ID (ISN)74360
CIS number 00-118
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Cocco P., Ward M.H., Dosemeci M.
Title Risk of stomach cancer associated with 12 workplace hazards: Analysis of death certificates from 24 states of the United States with the aid of job exposure matrices
Bibliographic information Nov. 1999, Vol.56, No.11, p.781-787. 20 ref.
Abstract To investigate the risk of gastric cancer associated with workplace exposures suspected as aetiological agents, a case-control study was conducted based on death certificates in the United States for 1984-96. Each occupation and industry was classified for exposure to asbestos, inorganic dust, metals, lead, polycyclic aromatic hydrocarbons (PAHs), nitrogen oxides, nitrosamines, sulphuric acid, fertilisers, herbicides, other pesticides and wood dust. Risk of stomach cancer showed a modest association with exposure to inorganic dust. Exposure to nitrosamines also showed a modest excess risk, but this was even smaller after adjusting for inorganic dust exposure. Risk of gastric cancer was not associated with any of the other workplace exposures. Non-differential misclassification of exposure may have caused negative findings in this study, and inorganic dust may be a partial surrogate for exposure to other unknown risk factors.
Descriptors (primary) mineral dust; nitroso amines; job-exposure relation; gastrointestinal cancer; harmful substances
Descriptors (secondary) herbicides; wood dust; aromatic hydrocarbons; lead; metals; nitrogen oxides; sulfuric acid; pesticides; fertilizers; polycyclic hydrocarbons; hazard evaluation; case-control study; asbestos
Document type D - Periodical articles
Country / State or ProvinceItaly; USA
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Gastrointestinal diseases