| Document ID (ISN) | 74243 |
| CIS number |
00-250 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1999 |
| Convention or series no. |
|
| Author(s) |
Laitinen S., Linnainmaa M., Laitinen J., Kiviranta H., Reiman M., Liesivuori J. |
| Title |
Endotoxins and IgG antibodies as indicators of occupational exposure to the microbial contaminants of metal-working fluids |
| Bibliographic information |
Oct. 1999, Vol.72, No.7, p.443-450. Illus. 24 ref. |
| Abstract |
To evaluate workers' exposure to microorganisms and bacterial endotoxins during the use of metal-working fluids (MWF), air and bulk sampling and biomonitoring of workers' serum IgG antibodies were used to estimate exposure at 18 workplaces. The types of emulsified MWF used were synthetic fluid, mineral oil or rape seed oil, in grinding, turning and drilling work. Endotoxin concentrations in air ranged from 0.04 to 600 ng/m3 when endotoxin levels in MWF were 0.03-25,000ng/m3. A high correlation was found between endotoxin levels and bacterial counts from MWF, as well as between total culturable bacteria and gram-negative bacteria concentrations in the air. MWF workers showed significantly higher IgG antibody responses to bacterial antigens than did controls. Results clearly show that in occupational hygiene measurements, endotoxins serve as excellent indicators of exposure to the microbial contaminants of MWF. IgG antibodies against antigens identified from workplace samples could be a practical tool for occupational health physicians. |
| Descriptors (primary) |
immunoglobulins; microorganisms; metalworking industry; cutting fluids; bacterial toxins |
| Descriptors (secondary) |
personal sampling; bacteria; fungi; exposure tests; dose-response relationship; determination in air; determination in blood; exposure evaluation |
| Document type |
D - Periodical articles |
| Country / State or Province | Finland |
| Subject(s) |
Metal production and metalworking
|
| Broad subject area(s) |
Biological hazards
|
| Browse category(ies) |
Metalworking industry
|
