Document ID (ISN) | 74234 |
CIS number |
00-110 |
ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
Year |
1999 |
Convention or series no. |
|
Author(s) |
Pezzotto S.M., Poletto L. |
Title |
Occupation and histopathology of lung cancer: A case-control study in Rosario, Argentina |
Bibliographic information |
Oct. 1999, Vol.36, No.4, p.437-443. Illus. 23 ref. |
Abstract |
Possible causes for the high male age-adjusted lung cancer mortality rate in Rosario City, Argentina (62.7 per 100,000) was investigated through a case-control study of 367 male lung cancer patients and 576 controls. The histological distribution detected was: squamous cell carcinoma 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no specified cell type 14%. Comparison with the group unlikely to be exposed to occupational carcinogens revealed a 60% increase in risk for the remaining occupations. Risks were high for drivers (odds ratio = 1.9), construction (OR = 2.5) and agricultural workers (OR = 1.8). Concerning squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR = 2.9) and mechanics (OR = 1.8). Smoking was not a substantial confounding factor. In conclusion, occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City. |
Descriptors (primary) |
lung cancer; job-exposure relation; industries; histopathology |
Descriptors (secondary) |
carcinogens; Argentina; carcinoma; smoking; agriculture; hazard evaluation; case-control study; construction industry; metalworking industry; drivers |
Document type |
D - Periodical articles |
Country / State or Province | Argentina |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Occupational medicine, epidemiology
|
Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar)
|