|Document ID (ISN)||74234|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Pezzotto S.M., Poletto L.
||Occupation and histopathology of lung cancer: A case-control study in Rosario, Argentina
||Oct. 1999, Vol.36, No.4, p.437-443. Illus. 23 ref.
||Possible causes for the high male age-adjusted lung cancer mortality rate in Rosario City, Argentina (62.7 per 100,000) was investigated through a case-control study of 367 male lung cancer patients and 576 controls. The histological distribution detected was: squamous cell carcinoma 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no specified cell type 14%. Comparison with the group unlikely to be exposed to occupational carcinogens revealed a 60% increase in risk for the remaining occupations. Risks were high for drivers (odds ratio = 1.9), construction (OR = 2.5) and agricultural workers (OR = 1.8). Concerning squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR = 2.9) and mechanics (OR = 1.8). Smoking was not a substantial confounding factor. In conclusion, occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City.
||lung cancer; job-exposure relation; industries; histopathology
||carcinogens; Argentina; carcinoma; smoking; agriculture; hazard evaluation; case-control study; construction industry; metalworking industry; drivers
||D - Periodical articles
|Country / State or Province||Argentina|
|Broad subject area(s)
||Occupational medicine, epidemiology
||Diseases of the respiratory system (except for pneumoconiosis & similar)