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Document ID (ISN)74234
CIS number 00-110
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Pezzotto S.M., Poletto L.
Title Occupation and histopathology of lung cancer: A case-control study in Rosario, Argentina
Bibliographic information Oct. 1999, Vol.36, No.4, p.437-443. Illus. 23 ref.
Abstract Possible causes for the high male age-adjusted lung cancer mortality rate in Rosario City, Argentina (62.7 per 100,000) was investigated through a case-control study of 367 male lung cancer patients and 576 controls. The histological distribution detected was: squamous cell carcinoma 39%, adenocarcinoma 34%, small cell carcinoma 13%, and other or no specified cell type 14%. Comparison with the group unlikely to be exposed to occupational carcinogens revealed a 60% increase in risk for the remaining occupations. Risks were high for drivers (odds ratio = 1.9), construction (OR = 2.5) and agricultural workers (OR = 1.8). Concerning squamous cell carcinoma, increased risks were observed in the metal industry, particularly in welders (OR = 2.9) and mechanics (OR = 1.8). Smoking was not a substantial confounding factor. In conclusion, occupational exposures partly account for the high lung cancer mortality rate among male residents of Rosario City.
Descriptors (primary) lung cancer; job-exposure relation; industries; histopathology
Descriptors (secondary) carcinogens; Argentina; carcinoma; smoking; agriculture; hazard evaluation; case-control study; construction industry; metalworking industry; drivers
Document type D - Periodical articles
Country / State or ProvinceArgentina
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)