|Document ID (ISN)||74232|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Sńverin R., Brńunlich A., Dahmann D., Enderlein G., Heuchert G.
||Diesel exhaust and lung cancer mortality in potash mining
||Oct. 1999, Vol.36, No.4, p.415-422. Illus. 15 ref.
||The association between lung cancer mortality and exposure to diesel exhaust was investigated in a cohort of 5,536 male potash miners who were followed from 1970 to 1994. Quantitative exposure was assessed from concentration measurements of the total carbon in personal dust samples, multiplied by years of exposure. Work histories and smoking habit data were obtained from medical company records. During the follow-up period, 424 deaths were recorded, including 133 of cancer, 38 of lung cancer. The relative risk of lung cancer between groups with high and low exposure was 2.2. With Cox regression, a relative risk of 1.7 for lung cancer after twenty years of exposure was found. Smoking was not a confounding factor. The principal finding is a doubling of relative lung cancer risk after twenty years of exposure in the workplaces with highest exposure. However, the observed elevation is nonsignificant even at a 90% level. Further follow-up is intended to enhance the study power.
||diesel engines; mortality; potash mining; exhaust gases; lung cancer
||personal sampling; healthy worker effect; Germany; respirable dust; long-term exposure; exposure evaluation; cohort study; long-term study; hazard evaluation
||D - Periodical articles
|Country / State or Province||Germany|
|Broad subject area(s)
||Mining and quarrying
Diseases of the respiratory system (except for pneumoconiosis & similar)