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Document ID (ISN)74231
CIS number 00-170
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Brüske-Hohlfeld I., Möhner M., Ahrens W., Pohlabeln H., Heinrich J., Kreuzer M., Jöckel K.H., Wichmann H.E.
Title Lung cancer risk in male workers occupationally exposed to diesel motor emissions in Germany
Bibliographic information Oct. 1999, Vol.36, No.4, p.405-414. Illus. 40 ref.
Abstract The association between occupational exposure to diesel motor emissions (DME) and lung cancer risk was studied by comparing cases with histologically or cytologically ascertained lung cancer in Germany and corresponding controls. Information about lifelong occupational and smoking history was obtained by questionnaire. Drivers of lorries, buses, taxis, diesel locomotives and forklift trucks, bulldozers, graders, excavators, and tractors were considered as exposed to DME and their cumulative exposure was estimated. The evaluation of lung cancer risk for all jobs with DME-exposure combined showed an odds ratio (OR) of 1.43. Most pronounced was the increase in lung cancer risk in heavy equipment operators (OR = 2.31). The risk of tractor drivers increased with length of employment and reached statistical significance for exposures longer than 30 years (OR = 6.81). The group of professional drivers showed an increased risk in West Germany (OR = 1.44), but not in East Germany (OR = 0.83). DME exposure in other traffic-related jobs was associated with an odds ratio of 1.53.
Descriptors (primary) diesel engines; lung cancer; hazard evaluation; exhaust gases; drivers
Descriptors (secondary) Germany; tractors; industrial trucks; exposure evaluation; case-control study; earthmoving equipment; long-term exposure; risk factors; geographical variables; job-exposure relation; road transport
Document type D - Periodical articles
Country / State or ProvinceGermany
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Risk evaluation
Diseases of the respiratory system (except for pneumoconiosis & similar)