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CISDOC database

Document ID (ISN)74015
CIS number 99-1952
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1997
Convention or series no.
Author(s) Johnsen C.R., Sorensen T.B., Larsen A.I., Secher A.B., Andreasen E., Kofoed G.S., Nielsen L.F., Gyntelberg F.
Title Allergy risk in an enzyme producing plant: A restrospective follow up study
Bibliographic information Sep. 1997, Vol.54, No.9, p.671-675. 30 ref.
Abstract A study of workers at a plant producing detergent and other industrial enzymes showed that sensitization occurred to all types of enzymes handled in the plant, most often in the production areas and laboratories. 8.8% of workers developed clinical enzyme allergy during the first three years of employment. Ranking diagnoses of enzyme allergy by severity, the frequency of asthma was 5.3%, rhinitis 3.0% and urticaria 0.6%. Half of the cases occurred within the first 15 months of exposure. Smoking was an independent risk factor for clinical enzyme allergy, while atopic predisposition at the time of engagement was not. Topics: allergic asthma; allergic respiratory disorders; allergic rhinitis; enzymes; individual susceptibility; long-term study; pulmonary function; radioallergosorbent test; risk factors; sensitization; smoking; urticaria.
Descriptors (primary) enzymes; sensitization; allergic respiratory disorders; urticaria
Descriptors (secondary) smoking; allergic rhinitis; allergic asthma; individual susceptibility; long-term study; radioallergosorbent test; risk factors; pulmonary function
Document type D - Periodical articles
Country / State or ProvinceDenmark
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Skin diseases