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Document ID (ISN)73399
CIS number 99-1241
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Milby T.H., Baselt R.C.
Title Hydrogen sulfide poisoning: Clarification of some controversial issues
Bibliographic information Feb. 1999, Vol.35, No.2, p.192-195. 34 ref.
Abstract Data on the toxicity of hydrogen sulfide are reviewed. It is concluded that: certain neurotoxic effects of exposure are probably due to a direct toxic effect on the brain, while others are almost certainly a result of hypoxia secondary to H2S-induced respiratory insufficiency; pulmonary oedema is a common consequence of poisoning and there is suggestive evidence of hyperactive airway responses in some individuals following brief H2S-induced unconsciousness (knockdown); criteria for acceptable community levels are very different than those governing occupational standards; urinary thiosulfate determinations can be useful for monitoring occupational exposure; and determination of sulfide ion concentrations in blood or major organs can be useful in corroborating a diagnosis of fatal H2S toxicity, but there are many pit-falls in collecting, storing, and analyzing tissue and fluid samples. Topics: acute poisoning; hydrogen sulfide; determination in blood; determination in urine; exposure tests; hypoxia; limitation of exposure; lung diseases; neurotoxic effects; pulmonary function; pulmonary oedema; thiosulfates; urine monitoring.
Descriptors (primary) neurotoxic effects; lung diseases; hydrogen sulfide; acute poisoning
Descriptors (secondary) thiosulfates; hypoxia; limitation of exposure; pulmonary function; pulmonary oedema; exposure tests; urine monitoring; determination in urine; determination in blood
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Inorganic sulfur compounds
Inorganic substances
Diseases of the respiratory system (except for pneumoconiosis & similar)