|Document ID (ISN)||73396|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Larsson B.M., Larsson K., Malmberg P., Mňrtensson L., Palmberg L.
||Airway responses in naive subjects to exposure in poultry houses: Comparison between cage rearing system and alternative rearing system for laying hens
||Feb. 1999, Vol.35, No.2, p.142-149. Illus. 25 ref.
||34 previously non-exposed subjects were exposed for 3h in confined poultry houses in three groups: one in a building with a cage rearing system and two in buildings with a cage-less system with either young hens and fresh bedding material or with older hens and old bedding material. Inhalable dust levels were approximately 4mg/m3 in the buildings with the cage-less system and 2mg/m3 in the building with cage rearing system; the endotoxin concentration was approximately 100ng/m3 in both systems. Bronchial responsiveness to methacholine increased approximately fivefold in all groups following exposure. The concentration of the proinflammatory cytokine interleukin-6 increased in nasal lavage fluid and in peripheral blood as a result of exposure. The number of leukocytes in peripheral blood increased only in the groups exposed among loose laying hens. Results indicate that among previously non-exposed subjects, that 3h exposure in confined buildings for egg production induces an acute inflammatory reaction in the upper airways and increased bronchial responsiveness. Topics: airborne dust; bacterial toxins; bronchial diseases; confined spaces; epidemiologic study; exposure evaluation; inflammations; interleukins; organic dust; poultry farming; pulmonary function; upper respiratory diseases.
||upper respiratory diseases; poultry farming; confined spaces; organic dust
||airborne dust; interleukins; bacterial toxins; epidemiologic study; inflammations; pulmonary function; exposure evaluation; bronchial diseases
||D - Periodical articles
|Country / State or Province||Sweden|
||Agriculture, fishing, animal husbandry
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)