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Document ID (ISN)73357
CIS number 99-1255
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Pan G., Takahashi K., Feng Y., Liu L., Liu T., Zhang S., Liu N., Okubo T., Goldsmith D.F.
Title Nested case-control study of esophageal cancer in relation to occupational exposure to silica and other dusts
Bibliographic information Mar. 1999, Vol.35, No.3, p.272-280. 33 ref.
Abstract In a nested case-control study of a cohort of industrial workers, 125 oesophageal cancer cases and 250 controls were identified from the death registry file. History of occupational exposure to various dusts was estimated. Occupational exposure to silica dust was the most important risk factor among all the variables investigated, with a 2.8-fold risk and a clear dose-response by length of exposure. Ingestion of silica particles after lung clearance may increase the risk of oesophageal cancer among workers exposed to silica. Topics: alcoholism; case-control study; coal dust; diet; dose-response relationship; exposure evaluation; job-exposure relation; mortality; oesophageal carcinoma; respirable dust; silica; steelworks.
Descriptors (primary) oesophageal carcinoma; silica; steelworks; respirable dust; mortality
Descriptors (secondary) coal dust; alcoholism; diet; job-exposure relation; case-control study; dose-response relationship; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceChina; Japan; USA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Gastrointestinal diseases
Iron and steel industry
Alcohol and drug abuse