ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)73015
CIS number 99-918
ISSN - Serial title 1076-2752 - Journal of Occupational and Environmental Medicine
Year 1999
Convention or series no.
Author(s) Prudhomme J.C., Bhatia R., Nutik J.M., Shusterman D.J.
Title Chest wall pain and possible rhabdomyolysis after chloropicrin exposure
Bibliographic information Jan. 1999, Vol.41, No.1, p.17-22. 23 ref.
Abstract Three cases are summarized in which persistent chest wall pain and elevations of creatine phosphokinase (CK) levels occurred after exposure to chloropicrin vapour in an agricultural chemicals facility. Both the severity of the symptoms and the degree of biochemical abnormality appeared to follow a dose-response relationship. Myoglobinuria, on the other hand, was not found. Elevation of CK after chloropicrin exposure has not previously been reported and may represent low-grade rhabdomyolysis. Workups performed after symptomatic chloropicrin exposure should include CK-level determination. Topics: agricultural chemicals; biochemical substances; chloropicrin; case study; enzyme activity determination; eye irritation; health hazards; muscular atrophy; muscular diseases; physiology of muscle; short-term exposure.
Descriptors (primary) agricultural chemicals; health hazards; chloropicrin
Descriptors (secondary) biochemical substances; eye irritation; case study; enzyme activity determination; muscular diseases; muscular atrophy; short-term exposure; physiology of muscle
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Agricultural chemicals