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Document ID (ISN)73004
CIS number 99-916
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1999
Convention or series no.
Author(s) Tulchinsky T.H., Ginsberg G.M., Iscovich J., Shihab S., Fischbein A., Richter E.D.
Title Cancer in ex-asbestos cement workers in Israel, 1953-1992
Bibliographic information Jan. 1999, Vol.35, No.1, p.1-8. Illus. 36 ref.
Abstract A cohort of 3,057 workers employed in an asbestos-cement plant located in Northern Israel was followed from 1953-1992 for incidence and mortality from cancer. In the years 1978-1992, the cohort had an elevated risk for all malignant neoplasms combined, lung cancer, mesothelioma, unspecified pleural cancer, and liver cancer. Risks for colo-rectal, bladder and renal cancers were less than expected. Risk for mesothelioma showed a sharp risk gradient with duration of exposure, increasing from 1 per 625 for those employed less than 2 years to 1 per 4.5 workers employed over 30 years. The ratio of mesothelioma to excess lung cancer cases was 2.9 to 1, or 3.6 to 1 if pleural cases of unspecified origin were included; the pleura to peritoneum ratio of verified mesothelioma cases was 20 to 1. It is suggested that this atypically high ratio of mesothelioma to excess lung cancer cases is the combined result of high past asbestos exposures in the workers and their low prior risk for lung cancer, and possibly, relatively early smoking cessation in relation to asbestos exposure. Topics: asbestos cement industry; asbestos; cancer; cohort study; Israel; liver cancer; long-term exposure; lung cancer; mesothelioma; morbidity; smoking.
Descriptors (primary) Israel; asbestos cement industry; cancer; asbestos
Descriptors (secondary) mesothelioma; smoking; morbidity; long-term exposure; liver cancer; cohort study; lung cancer
Document type D - Periodical articles
Country / State or ProvinceIsrael
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Asbestos
Cement and concrete