| Document ID (ISN) | 72879 |
| CIS number |
99-880 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1998 |
| Convention or series no. |
|
| Author(s) |
Lai J.S., Kwo H.W., Liao F.C., Lien C.H. |
| Title |
Sister chromatid exchange induced by chromium compounds in human lymphocytes |
| Bibliographic information |
Nov. 1998, Vol.71, No.8, p.550-553. Illus. 16 ref. |
| Abstract |
In a study of chromium and nickel-chromium electroplating workers, blood and urine chromium concentrations were highest among chromium workers, next highest among nickel-chromium workers and lowest among a non-exposed control group. After adjustment for smoking, values of sister chromatid exchange (SCE)/cell followed a similar pattern. Among smokers with high levels of chromium exposure, a synergistic effect resulted: percentages of high-frequency cells were higher in this group than in any other. Analysis of SCE in lymphocytes is useful for the evaluation of the biological effects of environmental mutagens. Topics: analysis of chromosome aberrations; nickel; case-control study; chromium and compounds; chromosome changes; determination in blood; determination in urine; electroplating; genetic effects; length of exposure; lymphocytes; mutagens; smoking; synergism. |
| Descriptors (primary) |
lymphocytes; chromium and compounds; chromosome changes; electroplating |
| Descriptors (secondary) |
mutagens; nickel; smoking; case-control study; genetic effects; determination in urine; length of exposure; determination in blood; analysis of chromosome aberrations; chromium; synergism |
| Document type |
D - Periodical articles |
| Country / State or Province | Taiwan (China) |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Genetic factors in reaction to exposures
Antifertility and prenatal effects
Surface treatment
|
