|Document ID (ISN)||72879|
|ISSN - Serial title
||0340-0131 - International Archives of Occupational and Environmental Health
|Convention or series no.
||Lai J.S., Kwo H.W., Liao F.C., Lien C.H.
||Sister chromatid exchange induced by chromium compounds in human lymphocytes
||Nov. 1998, Vol.71, No.8, p.550-553. Illus. 16 ref.
||In a study of chromium and nickel-chromium electroplating workers, blood and urine chromium concentrations were highest among chromium workers, next highest among nickel-chromium workers and lowest among a non-exposed control group. After adjustment for smoking, values of sister chromatid exchange (SCE)/cell followed a similar pattern. Among smokers with high levels of chromium exposure, a synergistic effect resulted: percentages of high-frequency cells were higher in this group than in any other. Analysis of SCE in lymphocytes is useful for the evaluation of the biological effects of environmental mutagens. Topics: analysis of chromosome aberrations; nickel; case-control study; chromium and compounds; chromosome changes; determination in blood; determination in urine; electroplating; genetic effects; length of exposure; lymphocytes; mutagens; smoking; synergism.
||lymphocytes; chromium and compounds; chromosome changes; electroplating
||mutagens; nickel; smoking; case-control study; genetic effects; determination in urine; length of exposure; determination in blood; analysis of chromosome aberrations; chromium; synergism
||D - Periodical articles
|Country / State or Province||Taiwan (China)|
||Toxic and dangerous substances
|Broad subject area(s)
||Antifertility and prenatal effects
Genetic factors in reaction to exposures