Document ID (ISN) | 72829 |
CIS number |
99-1002 |
ISSN - Serial title |
0355-3140 - Scandinavian Journal of Work, Environment and Health |
Year |
1997 |
Convention or series no. |
|
Author(s) |
Vanhanen M., Tuomi T., Nordman H., Tupasela O., Holmberg P.C., Miettinen M., Mutanen P., Leisola M. |
Title |
Sensitization to industrial enzymes in enzyme research and production |
Bibliographic information |
Oct. 1997, Vol.23, No.5, p.385-391, 18 ref. |
Abstract |
A cross-sectional study among 173 employees in two plants producing industrial enzymes and in their product development and research laboratories confirmed that industrial enzymes are potent sensitizers. The handling of dry enzymes in laboratory work may cause sensitization. Sensitization may even follow minute degrees of exposure, such as among office personnel. Atopics are more susceptible than nonatopics, but nonatopics are also clearly at risk. The demonstrated exposure-response relationship observed for enzyme sensitization and for respiratory symptoms during work emphasizes the need for and advantages of proper exposure control. Topics: allergens; allergy tests; amylase; biotechnology industry; dose-response relationship; dyspnoea; enzymes; individual susceptibility; rhinitis; sensitization. |
Descriptors (primary) |
enzymes; sensitization; biotechnology industry |
Descriptors (secondary) |
allergens; rhinitis; amylase; dose-response relationship; allergy tests; individual susceptibility; dyspnoea |
Document type |
D - Periodical articles |
Country / State or Province | Finland |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Biological hazards
|
Browse category(ies) |
Biotechnology industry
|