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Document ID (ISN)72829
CIS number 99-1002
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1997
Convention or series no.
Author(s) Vanhanen M., Tuomi T., Nordman H., Tupasela O., Holmberg P.C., Miettinen M., Mutanen P., Leisola M.
Title Sensitization to industrial enzymes in enzyme research and production
Bibliographic information Oct. 1997, Vol.23, No.5, p.385-391, 18 ref.
Abstract A cross-sectional study among 173 employees in two plants producing industrial enzymes and in their product development and research laboratories confirmed that industrial enzymes are potent sensitizers. The handling of dry enzymes in laboratory work may cause sensitization. Sensitization may even follow minute degrees of exposure, such as among office personnel. Atopics are more susceptible than nonatopics, but nonatopics are also clearly at risk. The demonstrated exposure-response relationship observed for enzyme sensitization and for respiratory symptoms during work emphasizes the need for and advantages of proper exposure control. Topics: allergens; allergy tests; amylase; biotechnology industry; dose-response relationship; dyspnoea; enzymes; individual susceptibility; rhinitis; sensitization.
Descriptors (primary) enzymes; sensitization; biotechnology industry
Descriptors (secondary) allergens; rhinitis; amylase; dose-response relationship; allergy tests; individual susceptibility; dyspnoea
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Biological hazards
Browse category(ies) Biotechnology industry