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Document ID (ISN)72747
CIS number 99-590
ISSN - Serial title 1341-9145 - Journal of Occupational Health
Year 1998
Convention or series no.
Author(s) Fukuda Y., Nagano M., Futatsuka M.
Title Occupational leukoderma in workers engaged in 4-(p-hydroxyphenyl)-2-butanone manufacturing
Bibliographic information Mar. 1998, Vol.40, No.2, p.118-122. Illus. 20 ref.
Abstract Three cases are presented of occupational leukoderma in the upper extremities of workers exposed to 4-(p-hydroxyphenyl)-2-butanone (HPB). In two of the cases, symptoms of contact dermatitis were present in the same areas before the occurrence of depigmentation. An epidemiologic study of 13 workers exposed to chemicals in the production of HPB showed that 9 had symptoms of dermatitis which were more severe in sunshine or hot weather. These facts suggest that HPB and/or the chemicals used in its manufacture have irritant and phototoxic potential. Topics: 4-(p-hydroxyphenyl)-2-butanone; chemical industry; epidemiologic study; leukoderma; pigmentation disorders.
Descriptors (primary) 4-(p-hydroxyphenyl)-2-butanone; leukoderma; chemical industry
Descriptors (secondary) epidemiologic study; pigmentation disorders
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Chemical industry