|Document ID (ISN)||72456|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Influence of the work environment in a Pb-Zn mine on the incidence of cytogenetic damage in miners
||Nov. 1998, Vol.34, No.5, p.455-463. Illus. 21 ref.
||In a study of cytogenetic damage in 120 miners occupationally exposed to radon and heavy metals in a lead-zinc mine, end points studied were structural chromosome aberrations, micronuclei and sister chromatid exchanges. Radon measurements were performed and the effective equivalent radiation doses over a 2-year period were calculated. The mean values of the percentage of structural chromosomal aberration frequency were 4.09% in miners, compared to 1.43% and 1.88% in two non-occupationally exposed control groups. The frequency of micronuclei and sister chromatid exchanges were also higher in the miners. Findings should be interpreted with regard to simultaneous exposure to radon and metals (lead, cadmium and zinc). Topics: analysis of chromosome aberrations; radon; lead; case-control study; chromosome changes; cytogenetic studies; determination in blood; exposure evaluation; genetic effects; lymphocytes; mining industry; smoking; workplace monitoring; zinc.
||radon; zinc; mining industry; genetic effects; chromosome changes; lead
||lymphocytes; workplace monitoring; smoking; analysis of chromosome aberrations; case-control study; determination in blood; cytogenetic studies; exposure evaluation
||D - Periodical articles
|Country / State or Province||Slovenia|
||Mines and quarries
|Broad subject area(s)
||Occupational medicine, epidemiology
||Antifertility and prenatal effects
Genetic factors in reaction to exposures
Mining and quarrying
Lead and compounds