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CISDOC database

Document ID (ISN)72456
CIS number 99-471
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1998
Convention or series no.
Author(s) Bilban M.
Title Influence of the work environment in a Pb-Zn mine on the incidence of cytogenetic damage in miners
Bibliographic information Nov. 1998, Vol.34, No.5, p.455-463. Illus. 21 ref.
Abstract In a study of cytogenetic damage in 120 miners occupationally exposed to radon and heavy metals in a lead-zinc mine, end points studied were structural chromosome aberrations, micronuclei and sister chromatid exchanges. Radon measurements were performed and the effective equivalent radiation doses over a 2-year period were calculated. The mean values of the percentage of structural chromosomal aberration frequency were 4.09% in miners, compared to 1.43% and 1.88% in two non-occupationally exposed control groups. The frequency of micronuclei and sister chromatid exchanges were also higher in the miners. Findings should be interpreted with regard to simultaneous exposure to radon and metals (lead, cadmium and zinc). Topics: analysis of chromosome aberrations; radon; lead; case-control study; chromosome changes; cytogenetic studies; determination in blood; exposure evaluation; genetic effects; lymphocytes; mining industry; smoking; workplace monitoring; zinc.
Descriptors (primary) radon; zinc; mining industry; genetic effects; chromosome changes; lead
Descriptors (secondary) lymphocytes; workplace monitoring; smoking; analysis of chromosome aberrations; case-control study; determination in blood; cytogenetic studies; exposure evaluation
Document type D - Periodical articles
Country / State or ProvinceSlovenia
Subject(s) Mines and quarries
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Genetic factors in reaction to exposures
Mining and quarrying
Inorganic substances
Lead and compounds