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CISDOC database

Document ID (ISN)70164
CIS number 97-1981
ISSN - Serial title 0098-7484 - Journal of the American Medical Association
Year 1997
Convention or series no.
Author(s) Calvert G.M., Steenland K., Palu S.
Title End-stage renal disease among silica-exposed gold miners: A new method for assessing incidence among epidemiologic cohorts
Bibliographic information Apr. 1997, Vol.277, No.15, p.1219-1223. 37 ref.
Abstract The incidence of end-stage renal disease (ESRD) was studied in a cohort of 2412 white male gold miners who had worked underground for at least one year. Exposure to silica was evaluated. Based on the 11 cohort members identified with ESRD, the risk in the cohort was elevated compared with the U.S. population. The risk was greatest for non-systemic ESRD and increased with years of employment underground. Results provide evidence that silica exposure is associated with increased risk for ESRD.
Descriptors (primary) silica; gold mining; renal diseases; morbidity
Descriptors (secondary) USA; nephrotoxic effects; length of exposure; cohort study
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Mines and quarries
Broad subject area(s) Chemical safety
Browse category(ies) Mining and quarrying
Diseases of the kidney and the urinary system