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CISDOC database

Document ID (ISN)70077
CIS number 97-2055
ISSN - Serial title 0959-8146 - British Medical Journal
Year 1997
Convention or series no.
Author(s) Zuckerman J.N., et al.
Title Immune response to a new hepatitis B vaccine in healthcare workers who had not responded to standard vaccine: Randomized double blind dose-response study
Bibliographic information Feb. 1997, Vol.314, No.7077, p.329-333. 32 ref.
Abstract The immunogenicity and reactogenicity of a new recombinant hepatitis B vaccine was evaluated in a cohort of 100 health care workers in whom currently licensed hepatitis B vaccines had not induced an immune response. 69 subjects seroconverted after a single dose of the new vaccine. After the booster vaccination, one other subject seroconverted, bringing the overall seroconversion rate to 70%. Factors affecting the immune response are discussed along with guidelines for immunization.
Descriptors (primary) infectious hepatitis; vaccination; health care personnel
Descriptors (secondary) immunogenic factors; case study
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Commerce, services, offices
Broad subject area(s) Biological hazards
Browse category(ies) Liver diseases
Health care services
Bacterial and parasitic diseases
Viral diseases (other than aids)