| Document ID (ISN) | 70064 |
| CIS number |
97-1948 |
| ISSN - Serial title |
1076-2752 - Journal of Occupational and Environmental Medicine |
| Year |
1997 |
| Convention or series no. |
|
| Author(s) |
Bhambhani Y., et al. |
| Title |
Effects of 10-ppm hydrogen sulfide inhalation in exercising men and women: Cardiovascular, metabolic and biochemical responses |
| Bibliographic information |
Feb. 1997, Vol.39, No.2, p.122-129. 36 ref. |
| Abstract |
The acute effects of 10-ppm hydrogen sulfide (H2S) inhalation, a concentration equal to the 8h TWA occupational exposure limit recommended by NIOSH, were examined in 28 healthy volunteers, after two 30-minute exercise sessions at 50% of their maximal oxygen uptake. A decrease in oxygen uptake, with a concomitant increase in blood lactate, was observed in men and women. No significant changes were observed in arterial blood parameters and cardiovascular responses. There was a tendency for muscle lactate to increase and citrate synthase to decrease in both sexes in the presence of H2S. These changes in oxygen uptake are probably caused by an inhibition of aerobic capacity of the exercising muscle. The appropriateness of the current occupational exposure limit for H2S should therefore be re-examined. |
| Descriptors (primary) |
hydrogen sulfide; oxygen intake; cardiovascular function tests; exercise tests; inhalation tests; permissible levels |
| Descriptors (secondary) |
Canada; lactates; human experiments; enzymological tests; determination in blood; determination in tissues; report on investigation |
| Document type |
D - Periodical articles |
| Country / State or Province | Canada |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Occupational exposure limits
Inorganic sulfur compounds
|
