| Document ID (ISN) | 69927 |
| CIS number |
97-1598 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1996 |
| Convention or series no. |
|
| Author(s) |
Apostoli P., et al. |
| Title |
Criteria and methods for the study of occupational exposure to antineoplastic drugs |
| Original title |
Criteri e metodi per lo studio dell'esposizione occupazionale a chemioterapici antiblastici [in Italian] |
| Bibliographic information |
May-June 1996, Vol.87, No.3, p.230-254. Illus. 60 ref. |
| Abstract |
Risk assessment and exposure evaluation of antineoplastic drugs are discussed from the point of view of environmental and biological monitoring. The problems of exposed health workers (pharmacists and nursing personnel) are emphasized. Guidelines are proposed on the basis of a check list adopted in some Italian hospitals. Work rooms, procedures, types and quantities of drugs and preventive measures must be monitored according to a standardized data collection scheme. Determination of cyclophosphamide, 5-fluorouracil and platinum coordination compounds used as tracers of drug mixtures is recommended in Italian hospitals. In annex: questionnaire for the evaluation of exposure to antineoplastic drugs; analytical methods for the determination of commonly used antineoplastic drugs. |
| Descriptors (primary) |
antineoplastic drugs; workplace monitoring; cyclophosphamide; platinum and compounds; hospitals; health care personnel; exposure tests; 5-fluorouracil |
| Descriptors (secondary) |
Italy |
| Document type |
D - Periodical articles |
| Country / State or Province | Italy |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Biological monitoring
Heterocyclic compounds
Health care services
|
