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Document ID (ISN)69257
CIS number 97-894
ISSN - Serial title 0019-8366 - Industrial Health
Year 1997
Convention or series no.
Author(s) Maeng S.H., Yu I.J.
Title Mutagenicity of 2-bromopropane
Bibliographic information Jan. 1997, Vol.35, No.1, p.87-95. Illus. 30 ref.
Abstract 2-bromopropane, a substitute for freon, is suspected to be responsible for an outbreak of reproductive dysfunctions among workers in an electronics factory. Bacterial mutation assays, chromosome aberration analysis in vitro and micronucleus tests in vivo were carried out to clarify the mutagenicity of 2-bromopropane. Results from reverse mutation assays using Salmonella typhimurium were positive and showed a dose-response relationship. The chromosome aberration tests and the micronucleus tests showed negative results.
Descriptors (primary) 2-bromopropane; mutagenic effects
Descriptors (secondary) animal experiments; analysis of chromosome aberrations; mutagenicity tests
Document type D - Periodical articles
Country / State or ProvinceKorea, Republic of
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Antifertility and prenatal effects
Halogenated hydrocarbons
Genetic factors in reaction to exposures