| Document ID (ISN) | 69257 |
| CIS number |
97-894 |
| ISSN - Serial title |
0019-8366 - Industrial Health |
| Year |
1997 |
| Convention or series no. |
|
| Author(s) |
Maeng S.H., Yu I.J. |
| Title |
Mutagenicity of 2-bromopropane |
| Bibliographic information |
Jan. 1997, Vol.35, No.1, p.87-95. Illus. 30 ref. |
| Abstract |
2-bromopropane, a substitute for freon, is suspected to be responsible for an outbreak of reproductive dysfunctions among workers in an electronics factory. Bacterial mutation assays, chromosome aberration analysis in vitro and micronucleus tests in vivo were carried out to clarify the mutagenicity of 2-bromopropane. Results from reverse mutation assays using Salmonella typhimurium were positive and showed a dose-response relationship. The chromosome aberration tests and the micronucleus tests showed negative results. |
| Descriptors (primary) |
2-bromopropane; mutagenic effects |
| Descriptors (secondary) |
animal experiments; analysis of chromosome aberrations; mutagenicity tests |
| Document type |
D - Periodical articles |
| Country / State or Province | Korea, Republic of |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Halogenated hydrocarbons
Genetic factors in reaction to exposures
Antifertility and prenatal effects
|
