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Document ID (ISN)69236
CIS number 97-957
ISBN(s) 91-7045-293-8
Year 1995
Convention or series no. Arbete och hälsa 1995:2
Author(s) Lundberg P.
Title The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals. 116. Glyoxal
Bibliographic information Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1995. 16p. 57 ref.
Abstract Glyoxal is a very reactive compound and it can react inside the cell with proteins, RNA and DNA. It is a potent allergen, and cross-sensitization has been shown between glyoxal, formaldehyde and glutaraldehyde. Although there are no human data, glyoxal should be regarded as an irritant to skin and mucous membranes. From animal studies, there are indications that glyoxal has a tumour-promoting effect in the glandular stomach of rats. The risk for human stomach cancer after inhalation of glyoxal must be considered to be very low. The critical effect is irritation of the skin and mucous membranes. The mutagenic properties might be a critical effect.
Descriptors (primary) glyoxal; Sweden
Descriptors (secondary) mutagenic effects; irritants; criteria document; animal experiments; determination of exposure limits; allergies
Document type F - Information notes, codes of practice, standards
Country / State or ProvinceSweden
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aldehydes
Genetic factors in reaction to exposures