|Document ID (ISN)||69236|
|Convention or series no.
||Arbete och hälsa 1995:2
||The Nordic Expert Group for Criteria Documentation of Health Risks from Chemicals. 116. Glyoxal
||Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1995. 16p. 57 ref.
||Glyoxal is a very reactive compound and it can react inside the cell with proteins, RNA and DNA. It is a potent allergen, and cross-sensitization has been shown between glyoxal, formaldehyde and glutaraldehyde. Although there are no human data, glyoxal should be regarded as an irritant to skin and mucous membranes. From animal studies, there are indications that glyoxal has a tumour-promoting effect in the glandular stomach of rats. The risk for human stomach cancer after inhalation of glyoxal must be considered to be very low. The critical effect is irritation of the skin and mucous membranes. The mutagenic properties might be a critical effect.
||mutagenic effects; irritants; criteria document; animal experiments; determination of exposure limits; allergies
||F - Information notes, codes of practice, standards
|Country / State or Province||Sweden|
||Toxic and dangerous substances
|Broad subject area(s)
Genetic factors in reaction to exposures