|Document ID (ISN)||69027|
|ISSN - Serial title
||0040-6376 - Thorax
|Convention or series no.
||Piitulainen E., Tornling G., Eriksson S.
||Effect of age and occupational exposure to airway irritants on lung function in non-smoking individuals with α1 antitrypsin deficiency (PiZZ)
||Mar. 1997, Vol.52, p.244-248. Illus. 16 ref.
||Severe α1-antitrypsin (AAT) deficiency (PiZZ) is associated with an increased risk of lung emphysema, especially in smokers. The aim of this study was to identify risk factors other than smoking for declining lung function. Lung function was studied in 225 self-reported never-smoking PiZZ subjects included in the Swedish AAT deficiency register. Lung function was poorer in men than in women. Among the PiZZ subjects, men reported occupational exposure to gases, fumes or dust more frequently than women. In those aged 50 or older, lung function declined. Asthmatic symptoms and occupational exposure to airway irritants appear to constitute additional risk factors for this condition.
||irritants; antitrypsin; risk factors; emphysema; respiratory function tests; smoking
||report on investigation; Sweden
||D - Periodical articles
|Country / State or Province||Sweden|
|Broad subject area(s)
||Occupational medicine, epidemiology
Diseases of the respiratory system (except for pneumoconiosis & similar)