|Document ID (ISN)||68898|
|ISSN - Serial title
||1351-0711 - Occupational and Environmental Medicine
|Convention or series no.
||Swaen G.M.H., Meijers J.M.M., Slangen J.J.M.
||Risk of gastric cancer in pneumoconiotic coal miners and the effect of respiratory impairment
||Sep. 1995, Vol.52, No.9, p.606-610. 15 ref.
||This study was carried out to investigate the mortality patterns in a group of 3790 coal miners. The study population had abnormal chest X-ray films at a routine medical examination that was performed in the 1950's. The total group of 3790 coal miners was followed up for mortality up to 1 January 1992. Total mortality in this group of coal miners was significantly higher than expected, mainly a reflection of the increase in mortality from non-malignant respiratory disease. Mortality from gastric cancer was also significantly increased. This risk of mortality from gastric cancer was confined to workers with no pneumoconiosis or only a mild from. Despite the strong relation to duration of employment and pneumoconiosis the group of workers with more severe manifestations of pneumoconiosis did not experience an excess in mortality from gastric cancer. This study confirms the earlier reported risk of gastric cancer in coal miners. Also it confirms the hypothesis that this risk of gastric cancer is limited to workers with a mild degree of pneumoconiosis or none. In workers with severe forms of pneumoconiosis the pulmonary clearance system is impaired in such a way that the inhaled coal dust does not reach the digestive tract.
||coal dust; mortality; pneumoconiosis; coal mining; hazard evaluation; carcinogenic effects; gastrointestinal cancer
||hazard criteria; long-term study; length of service; respirable dust
||D - Periodical articles
|Country / State or Province||Netherlands|
||Mines and quarries
|Broad subject area(s)
||Occupational medicine, epidemiology
||Mining and quarrying