| Document ID (ISN) | 68756 |
| CIS number |
97-482 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1994 |
| Convention or series no. |
|
| Author(s) |
Piolatto G., Pira E., Meliga F. |
| Title |
The use and usefulness of multistage models of carcinogenesis in cohort studies |
| Original title |
L'uso e l'utilità dei modelli multistage di cancerogenesi negli studi di coorte [in Italian] |
| Bibliographic information |
Jan.-Feb. 1994, Vol.85, No.1, p.78-83. 11 ref. |
| Abstract |
This is a review of multistage models applied to data on exposure to aromatic amines and bladder cancer mortality. The results suggest that aromatic amines act on more than one stage of the carcinogenic process, most probably on both early and late stages. The effect on late stages implies a decreasing risk after cessation of exposure, and in this case discontinuing it can be useful; an effect on early stages, instead, indicates the necessity of intensive medical surveillance even after cessation of exposure. |
| Descriptors (primary) |
aromatic amines; bladder tumour; epidemiology; mortality |
| Descriptors (secondary) |
mathematical models |
| Document type |
D - Periodical articles |
| Country / State or Province | Italy |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Aromatic amines
Epidemiology
Diseases of the kidney and the urinary system
|
