| Document ID (ISN) | 68755 |
| CIS number |
97-481 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1994 |
| Convention or series no. |
|
| Author(s) |
Caporaso N.E., Landi M.T. |
| Title |
Molecular epidemiology: A new perspective for the study of toxic exposures in man. A consideration of the influence of genetic susceptibility factors on risk in different lung cancer histologies |
| Bibliographic information |
Jan.-Feb. 1994, Vol.85, No.1, p.68-77. 45 ref. |
| Abstract |
Epidemiologic evidence for genetic susceptibility factors in tobacco-related cancer is suggestive but not determinant. Variability in results depends on: assay misclassification, non-correspondence of phenotype/genotype in certain subjects, disease heterogeneity, exposure variation, ethnic and racial variation. Future studies should concentrate on the presence of multiple genetic markers. The observation that the tobacco-cancer association is weaker for adenocarcinoma than for the other lung cancers suggests some interaction of the genetic trait with exposure to tobacco smoking. |
| Descriptors (primary) |
smoking; individual susceptibility; genetic effects; lung cancer |
| Descriptors (secondary) |
carcinogenic effects; epidemiology |
| Document type |
D - Periodical articles |
| Country / State or Province | Italy |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Antifertility and prenatal effects
Genetic factors in reaction to exposures
Smoking
Diseases of the respiratory system (except for pneumoconiosis & similar)
|
