|Document ID (ISN)||68755|
|ISSN - Serial title
||0025-7818 - Medicina del lavoro
|Convention or series no.
||Caporaso N.E., Landi M.T.
||Molecular epidemiology: A new perspective for the study of toxic exposures in man. A consideration of the influence of genetic susceptibility factors on risk in different lung cancer histologies
||Jan.-Feb. 1994, Vol.85, No.1, p.68-77. 45 ref.
||Epidemiologic evidence for genetic susceptibility factors in tobacco-related cancer is suggestive but not determinant. Variability in results depends on: assay misclassification, non-correspondence of phenotype/genotype in certain subjects, disease heterogeneity, exposure variation, ethnic and racial variation. Future studies should concentrate on the presence of multiple genetic markers. The observation that the tobacco-cancer association is weaker for adenocarcinoma than for the other lung cancers suggests some interaction of the genetic trait with exposure to tobacco smoking.
||smoking; individual susceptibility; genetic effects; lung cancer
||carcinogenic effects; epidemiology
||D - Periodical articles
|Country / State or Province||Italy|
|Broad subject area(s)
||Occupational medicine, epidemiology
||Antifertility and prenatal effects
Genetic factors in reaction to exposures
Diseases of the respiratory system (except for pneumoconiosis & similar)