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Document ID (ISN)68590
CIS number 97-458
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1996
Convention or series no.
Author(s) Brumen V., Horvat D.
Title Work environment influence on cytostatics-induced genotoxicity in oncologic nurses
Bibliographic information July 1996, Vol.30, No.1, p.67-71. Bibl.ref.
Abstract The aim of this study was to examine the influence of workplace conditions on chromosomal damage incidence in nurses handling cytostatics. The study involved two groups of 17 oncologic nurses each and the same number of matched controls. Sister chromatid exchange method (SCE) was used for genotoxicity assessment. In the group of nurses provided with a safe working environment, the SCE-frequency was insignificantly increased when compared with the controls, although wide SCE-ranges were obtained. By contrast, in the group of nurses provided with neither such an environment nor with the appropriate personal protective equipment, the SCE-frequency was significantly higher, not only compared with the control group, but also with the first group of nurses.
Descriptors (primary) cytostatic drugs; chromosome changes; nursing personnel; conditions of work
Descriptors (secondary) workplaces; cancer; cross-sectional study; genetic effects; hospitals; health care personnel; personal protective equipment
Document type D - Periodical articles
Country / State or ProvinceCroatia
Subject(s) Commerce, services, offices
Broad subject area(s) General safety, health and conditions of work
Browse category(ies) Health care services
Genetic factors in reaction to exposures
Antifertility and prenatal effects