|Document ID (ISN)||68589|
|ISSN - Serial title
||0271-3586 - American Journal of Industrial Medicine
|Convention or series no.
||Vrca A., Karačić V., Božičević D., Božikov V., Malinar M.
||Brainstem auditory evoked potentials in individuals exposed to long-term low concentrations of toluene
||July 1996, Vol.30, No.1, p.62-66. 23 ref.
||97-0573.pdf [in English]
||The aim of this study was to evaluate the effect of long-term exposure to low concentration of toluene on the central nervous system by using brainstem auditory evoked potentials (BAEPs). Forty nine printing plant workers occupationally exposed to low concentrations of toluene for an average of 20.3 years and 59 non-exposed controls were examined. The level of exposure to toluene was evaluated by defining the concentration of toluene in peripheral blood and the concentration of hippuric acid and ortho-cresol in urine. In the group of exposed workers, a significant decrease in all wave amplitudes examined, a significant prolongation of P1 wave latency and an increased interval of interpeak latencies (P3-P5) were found. This indicates that the extramedullary and high medullary part of the auditory pathway are biologically most frequently affected by long-term exposure to low concentrations of toluene.
||neurotoxic effects; audiometric tests; toluene; printing industry
||diseases of central nervous system; exposure tests; long-term exposure; exposure evaluation
||D - Periodical articles
|Country / State or Province||Croatia|
||Paper-making and printing
|Broad subject area(s)
||Diseases of the nervous system
Printing, photography and photocopying industry