| Document ID (ISN) | 68583 |
| CIS number |
97-557 |
| ISSN - Serial title |
0271-3586 - American Journal of Industrial Medicine |
| Year |
1996 |
| Convention or series no. |
|
| Author(s) |
Kreiss K., Mroz M.M., Newman L.S., Martyny J., Zhen B. |
| Title |
Machining risk of beryllium disease and sensitization with median exposures below 2µg/m3 |
| Bibliographic information |
July 1996, Vol.30, No.1, p.16-25. 11 ref. |
| Abstract |
The prevalence of beryllium sensitization in relation to work process and beryllium exposure measurements was examined in a beryllia ceramics plant that had operated since 1980. 97.8% of the workforce was interviewed, beryllium sensitization was ascertained with the beryllium lymphocyte proliferation blood test and historical industrial hygiene measurements were reviewed. Of eight beryllium-sensitized employees, six had granulomatous disease on transbronchial lung biopsy. Machinists had a sensitization rate of 14.3% compared to a rate of 1.2% among other employees. Daily weighted average (DWA) estimates of exposure for machining processes also exceeded estimates for other work processes in that time period, with a median DWA of 0.9µg/m3. Machining process DWAs accounted for the majority of DWAs exceeding the 2.0µg/m3 OSHA standard, with 8.1% of machining DWAs above the standard. It is concluded that lowering machining process-related exposures may be important in the lowering of risk of developing beryllium disease. |
| Descriptors (primary) |
beryllium; sensitization; pottery industry; lung diseases |
| Descriptors (secondary) |
threshold limit values; dose-response relationship; pulmonary granulomatosis |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Diseases of the respiratory system (except for pneumoconiosis & similar)
Glass, pottery and related materials
|
