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Document ID (ISN)68319
CIS number 97-185
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1995
Convention or series no.
Author(s) Maizlish N.A., Parra G., Feo O.
Title Neurobehavioural evaluation of Venezuelan workers exposed to inorganic lead
Bibliographic information 1995, Vol.52, p.408-414. Illus. 27 ref.
Abstract To assess neurobehavioural effects of low exposure to lead, 43 workers from a lead smelter and 45 workers from a glass factory were evaluated with the World Health Organization neurobehavioural core test battery (NCTB) in a cross-sectional study. Historical blood lead concentrations were used to classify exposure based on current, peak and time-weighted average. Although the exposed workers performed less well than the non-exposed in 10 of 14 response variables, only profile of mood states tension-anxiety, hostility and depression mood scales showed a significantly poorer dose-response relation with blood lead concentration in multiple linear regression models that included age, education and alcohol intake as covariates. The frequency of symptoms of anger, depression, fatigue and joint pain were also significantly increased in the exposed group. This study is consistent with the larger body of neurobehavioural research of low occupational exposure to lead.
Descriptors (primary) neurotoxic effects; nervous function tests; foundries; neuropsychic effects; glass industry; lead
Descriptors (secondary) conditions of exposure; WHO; anxiety; depressive neurosis; fatigue; Venezuela; behaviour study; dose-response relationship; determination in blood; exposure tests; developing countries; cross-sectional study
Document type D - Periodical articles
Country / State or ProvinceUSA; Venezuela
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Inorganic substances
Glass, pottery and related materials
Foundries, metalcasting and forging operations
Lead and compounds