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Document ID (ISN)68031
CIS number 96-2197
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1993
Convention or series no.
Author(s) Case R.A.M., Hosker M.E., McDonald D.B., Pearson J.T.
Title Tumours of the urinary bladder in workmen engaged in the manufacture and use of certain dyestuff intermediates in the British chemical industry
Bibliographic information May 1993, Vol.50, No.5, p.389-411. Illus.
Abstract Editor's choice: reprint of a classic paper originally published in 1954 (BJIM 11: 75-96). It presents the results of a follow up on more that 4600 men in the British chemical industry from 1920 to 1949. The overall risk of dying from bladder cancer was about 30 times that of the general population and contact with benzidine, alpha-naphthylamine or beta-napthylamine (but not aniline) in either manufacture or use was liable to cause an excess number of tumours. Furthermore, this study confirms what was known for other occupational tumours, that is, that both onset and death occurred at an earlier age than in non-occupational cases.
Descriptors (primary) chemical industry; bladder tumour; dyes; United Kingdom
Descriptors (secondary) 1-naphthylamine; aniline; 2-naphthylamine; benzidine; long-term study; age-linked differences; epidemiologic study
Document type D - Periodical articles
Country / State or ProvinceUnited Kingdom
Subject(s) Chemicals, plastics and rubber
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the kidney and the urinary system
Chemical industry