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Document ID (ISN)67883
CIS number 96-2167
ISSN - Serial title 0012-3692 - Chest
Year 1996
Convention or series no.
Author(s) Lemière C., Cloutier Y., Perrault G., Drolet D., Cartier A., Malo J.L.
Title Closed-circuit apparatus for specific inhalation challenges with an occupational agent, formaldehyde, in vapor form
Bibliographic information June 1996, Vol.109, No.6, p.1631-1635. Illus. 17 ref.
Abstract Since occupational agents responsible for asthma are frequently present in the workplace as vapours, an apparatus was developed for bronchial provocation tests on subjects exposed to formaldehyde and other chemicals in vapour form. This apparatus was assessed in four subjects suspected of having formaldehyde-induced asthma or alveolitis. The instrument consists of four parts: a gas generator, an exposure chamber, a monitor and an automated regulatory system. The concentrations of formaldehyde were increased from 0.5-1mg/m3 to 3mg/m3, without overshooting the concentration of 3mg/m3 (STEL in Canada). It was observed that target concentrations took a few minutes to be reached, but, once they were obtained, delivered concentrations were stable. The described method should be further validated and extended to other occupational agents.
Descriptors (primary) formaldehyde; inhalation tests; closed circuit breathing apparatus; asthma
Descriptors (secondary) threshold limit values; description of technique; Canada; description of equipment
Document type D - Periodical articles
Country / State or ProvinceCanada
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Respiratory protection