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CISDOC database

Document ID (ISN)67731
CIS number 96-1779
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1995
Convention or series no.
Author(s) Fu H., Boffetta P.
Title Cancer and occupational exposure to inorganic lead compounds: A meta-analysis of published data
Bibliographic information Feb. 1995, Vol.52, No.2, p.73-81. 56 ref.
Abstract This study reviews and summarizes the epidemiological evidence on the carcinogenicity of occupational exposure to organic lead. The findings from workers with heavy exposure to lead provided some evidence to support the hypothesis of an association between cancers of the stomach and lung and exposure to lead. The main limitation of the present analysis is that the excess risks do not take account of potential confounders, because little information was available for other occupational exposures, smoking and dietary habits. To some extent, the risk of lung cancer might be explained by confounders such as tobacco smoking and exposure to other occupational carcinogens. The excess risk of stomach cancer may also be explained, at least in part, by non-occupational factors. For bladder and kidney cancers, the excess risks are only suggestive of a true effect because of possible publication bias.
Descriptors (primary) lead and compounds; carcinogenic effects; health hazards; cancer
Descriptors (secondary) literature survey; carcinogens; lead; smoking; synergism; lung cancer; gastrointestinal cancer; epidemiologic study; bladder tumour
Document type D - Periodical articles
Country / State or ProvinceChina; WHO
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Lead and compounds
Inorganic substances