ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)67493
CIS number 96-1793
ISBN(s) 3-7776-0709-6
Year 1996
Convention or series no. BUA Report 132
Gesellschaft Deutscher Chemiker (GDCh) - Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Title 4,4-Methylenedianiline
Bibliographic information S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1996. xv, 125p. 346 ref. Price: DEM 72.00.
Abstract Conclusions of this criteria document, translation of a report finalized in December 1993: 4,4-methylenedianiline is well absorbed through the skin. In humans it has a mainly hepato- and nephrotoxic effect; two studies describe degenerative changes of the retina and electrocardiographic changes. There are also reports of sensitization in humans. Animal studies indicate that the substance is carcinogenic; studies of genotoxicity showed mainly positive results.
Descriptors (primary) methylenedianiline; ecotoxicology; toxicology; Germany
Descriptors (secondary) toxic effects; literature survey; carcinogens; hepatotoxic effects; criteria document; sensitizers; nephrotoxic effects; legislation; translation; skin absorption
Document type E - Books, reports, proceedings
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic amines
Pollution control