|Document ID (ISN)||67493|
|Convention or series no.
||BUA Report 132
Gesellschaft Deutscher Chemiker (GDCh) - Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
||S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1996. xv, 125p. 346 ref. Price: DEM 72.00.
||Conclusions of this criteria document, translation of a report finalized in December 1993: 4,4-methylenedianiline is well absorbed through the skin. In humans it has a mainly hepato- and nephrotoxic effect; two studies describe degenerative changes of the retina and electrocardiographic changes. There are also reports of sensitization in humans. Animal studies indicate that the substance is carcinogenic; studies of genotoxicity showed mainly positive results.
||methylenedianiline; ecotoxicology; toxicology; Germany
||toxic effects; literature survey; carcinogens; hepatotoxic effects; criteria document; sensitizers; nephrotoxic effects; legislation; translation; skin absorption
||E - Books, reports, proceedings
|Country / State or Province||Germany|
||Toxic and dangerous substances
|Broad subject area(s)