Document ID (ISN) | 67152 |
CIS number |
96-1317 |
ISSN - Serial title |
1219-1221 - Central European Journal of Occupational and Environmental Medicine |
Year |
1996 |
Convention or series no. |
|
Author(s) |
Köteles G. |
Title |
The human lymphocyte micronucleus assay. A review of its applicabilities in occupational and environmental medicine |
Bibliographic information |
1996, Vol.2, No.1, p.12-30. Illus. 78 ref. |
Abstract |
The use of the micronucleus assay from human lymphocytes in the detection of cytogenic changes is reviewed. Base values of human micronucleus frequencies obtained from a number of studies are tabulated and discussed, and dose-response data relating to the effect of ionizing radiation on these frequencies are reviewed. The use of the micronucleus test in evaluating the genotoxic effects of chemicals (heavy metals, polycyclic aromatic hydrocarbons, organic solvents, clastogenic agents) and in assessing the efficiency of radioprotective compounds is also discussed. |
Descriptors (primary) |
ionizing radiation; mutagenic effects; cytogenetic studies; lymphocytes; mutagens |
Descriptors (secondary) |
literature survey; polycyclic hydrocarbons; organic solvents |
Document type |
D - Periodical articles |
Country / State or Province | Hungary |
Subject(s) |
Medicine, hygiene and first aid
|
Broad subject area(s) |
Occupational medicine, epidemiology
|
Browse category(ies) |
Antifertility and prenatal effects Ionizing radiation Genetic factors in reaction to exposures
|