ILO Home
Go to the home page
Site map | Contact us Français | Español

CISDOC database

Document ID (ISN)67152
CIS number 96-1317
ISSN - Serial title 1219-1221 - Central European Journal of Occupational and Environmental Medicine
Year 1996
Convention or series no.
Author(s) Köteles G.
Title The human lymphocyte micronucleus assay. A review of its applicabilities in occupational and environmental medicine
Bibliographic information 1996, Vol.2, No.1, p.12-30. Illus. 78 ref.
Abstract The use of the micronucleus assay from human lymphocytes in the detection of cytogenic changes is reviewed. Base values of human micronucleus frequencies obtained from a number of studies are tabulated and discussed, and dose-response data relating to the effect of ionizing radiation on these frequencies are reviewed. The use of the micronucleus test in evaluating the genotoxic effects of chemicals (heavy metals, polycyclic aromatic hydrocarbons, organic solvents, clastogenic agents) and in assessing the efficiency of radioprotective compounds is also discussed.
Descriptors (primary) ionizing radiation; mutagenic effects; cytogenetic studies; lymphocytes; mutagens
Descriptors (secondary) literature survey; polycyclic hydrocarbons; organic solvents
Document type D - Periodical articles
Country / State or ProvinceHungary
Subject(s) Medicine, hygiene and first aid
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Antifertility and prenatal effects
Ionizing radiation
Genetic factors in reaction to exposures