ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)66924
CIS number 96-845
ISSN - Serial title 0002-9262 - American Journal of Epidemiology
Year 1996
Convention or series no.
Author(s) Correa A., Gray R.H., Cohe R., Rothman N., Shah F., Seacat H., Corn M.
Title Ethylene glycol ethers and risks of spontaneous abortion and subfertility
Bibliographic information Apr. 1996, Vol.143, No.7, p.707-717. 38 ref.
Abstract Occupational exposures to ethylene glycol ethers (EGE) are of concern since their reproductive toxicity has been well documented in animal studies. A retrospective cohort study was conducted among workers at two semiconductor manufacturing plants in the eastern United States in 1980-1989. Assessment of potential exposure to mixtures containing EGE was based on reported processes and company records. Among female workers potential exposure to mixtures containing EGE was associated with increased risks of spontaneous abortion and subfertility. Both of these risks exhibited a dose-response relation. Among spouses of male worker potentially exposed to mixtures containing EGE, there was no increased risk of spontaneous abortion, but a nonsignificant increased risk of subfertility was ascertained.
Descriptors (primary) antifertility effects; glycol ethers; occupational medicine; electronics industry; abortion
Descriptors (secondary) USA; exposure records; cohort study
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Manufacturing of electrical appliances and equipment
Electronics industry
Genetic factors in reaction to exposures
Diseases of the reproductive system
Antifertility and prenatal effects
Glycol ethers