| Document ID (ISN) | 66924 |
| CIS number |
96-845 |
| ISSN - Serial title |
0002-9262 - American Journal of Epidemiology |
| Year |
1996 |
| Convention or series no. |
|
| Author(s) |
Correa A., Gray R.H., Cohe R., Rothman N., Shah F., Seacat H., Corn M. |
| Title |
Ethylene glycol ethers and risks of spontaneous abortion and subfertility |
| Bibliographic information |
Apr. 1996, Vol.143, No.7, p.707-717. 38 ref. |
| Abstract |
Occupational exposures to ethylene glycol ethers (EGE) are of concern since their reproductive toxicity has been well documented in animal studies. A retrospective cohort study was conducted among workers at two semiconductor manufacturing plants in the eastern United States in 1980-1989. Assessment of potential exposure to mixtures containing EGE was based on reported processes and company records. Among female workers potential exposure to mixtures containing EGE was associated with increased risks of spontaneous abortion and subfertility. Both of these risks exhibited a dose-response relation. Among spouses of male worker potentially exposed to mixtures containing EGE, there was no increased risk of spontaneous abortion, but a nonsignificant increased risk of subfertility was ascertained. |
| Descriptors (primary) |
antifertility effects; glycol ethers; occupational medicine; electronics industry; abortion |
| Descriptors (secondary) |
USA; exposure records; cohort study |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Manufacturing of electrical appliances and equipment
Electronics industry
Genetic factors in reaction to exposures
Diseases of the reproductive system
Antifertility and prenatal effects
Glycol ethers
|
