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Document ID (ISN)66830
CIS number 96-800
ISSN - Serial title 1351-0711 - Occupational and Environmental Medicine
Year 1994
Convention or series no.
Author(s) Hjortsberg U., ěrbaek P., Arborelius M.J., Karlsson J.E.
Title Upper airway irritation and small airways hyperreactivity due to exposure to potassium aluminium tetrafluoride flux - An extended case report
Bibliographic information Oct. 1994, Vol.51, No.10, p.706-709. 15 ref.
Abstract Twenty-two workers, exposed to potassium aluminium tetrafluoride used as flux for soldering aluminium, were studied as clinical outpatients for symptoms of irritation of the nose, eye, skin and airways. Sixteen volunteered for spirometry with methacholine provocation test including a test for small airways function by volume of trapped gas (VTG). Symptoms of airways irritation diminished in all subjects after flux exposure ended. The FEV1 was within the normal range in 16 of 17 subjects before the methacholine provocation test. The FEV1 decreased by ≥20% in two out of 16 subjects after the 0.1% methacholine provocation and after inhalation of methacholine, eight out of 16 subjects (50%) had an abnormal increase of VTG indicating hyperreactivity in small airways. Potassium aluminium tetrafluoride flux seems to induce an increase of bronchial reactivity in small airways. A setting of an occupational standard is proposed.
Descriptors (primary) diseases of eyes and related structures; diseases of nose and sinuses; potassium aluminium tetrafluoride; soldering flux; upper respiratory diseases; skin diseases; irritation
Descriptors (secondary) draft standard; case study; exposure tests; spirometry; maximal expiratory flow
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the respiratory system (except for pneumoconiosis & similar)
Diseases of the eye and vision damage
Halogens and their inorganic compounds
Inorganic substances
Skin diseases