|Document ID (ISN)||66813|
|ISSN - Serial title
||0007-1072 - British Journal of Industrial Medicine
|Convention or series no.
||Dodson R.F., O'Sullivan M., Corn C.J., Garcia J.G.N., Stocks J.M., Griffith D.E.
||Analysis of ferruginous bodies in bronchoalveolar lavage from foundry workers
||Nov. 1993, Vol.50, No.11, p.1032-1038. Illus. 24 ref.
||96-0625.pdf [in English]
||Classical ferruginous bodies in tissue samples are considered to be markers of past exposure to asbestos. Recent studies have shown that the presence of ferruginous bodies in bronchoalveolar lavage (BAL) fluid correlates with past exposure to asbestos and offers a more sensitive reference than occupational history. Lavage samples from five subjects who had worked in foundries were evaluated by light microscopy for the presence of ferruginous bodies and by transmission electron microscopy for both characterization of the uncoated fibre burden and analysis of the cores of the ferruginous bodies. All samples at lower magnification (light microscopy (200 x)) contained ferruginous bodies. At higher magnification (400 x), a separate population from this group could be identified by the presence of a thin black ribbon. Transmission electron microscopy of the core materials of ferruginous bodies and comparable uncoated particulates supported the reliability of higher magnification light microscopy for distinguishing most of these non-asbestos cores.
||asbestos; ferruginous bodies; bronchopulmonary lavage; exposure tests; foundries; diagnosis
||pulmonary fibrosis; asbestosis; asbestos bodies; comparative study; transmission electron microscopy; light microscopy; bronchoscopy; exposure evaluation
||D - Periodical articles
|Country / State or Province||USA|
||Metal production and metalworking
|Broad subject area(s)
||Occupational medicine, epidemiology
||Foundries, metalcasting and forging operations