| Document ID (ISN) | 66647 |
| CIS number |
96-837 |
| ISSN - Serial title |
0160-2748 - Neurotoxicology |
| Year |
1994 |
| Convention or series no. |
|
| Author(s) |
Lille F., Margules S., Fournier E., Dally S., Garnier R. |
| Title |
Effects of occupational lead exposure on motor and somatosensory evoked potentials |
| Bibliographic information |
Fall 1994, Vol.15, No.3, p.679-683. Illus. 12 ref. |
| Abstract |
In order to determine the exact effects of inorganic lead compounds on the nervous system, 17 occupationally exposed men were tested for Motor Electric Potentials (MEPs) of the abductor policis brevis muscles with transcranial, cervical root and peripheral electrical stimulations, for Somatosensory Evoked Potentials (SEPs) of the median and tibial posterior nerves, and for electromyography (EMG). Sixteen of the 17 subjects exhibited electrophysiological abnormalities, occurring at both peripheral and central levels for the somatosensory as well as for the motor systems. Lead exposure was also related to decreased sensory and motor peripheral conduction velocities, increased motor central conduction time, and delayed cortical P22 SEPs component that could be interpreted as a sensory-motor cortical dysfunction. The respective contributions of MEPs and SEPs are compared to clinical, biological and EMG examinations in the evaluation of the neurotoxic effects of inorganic lead compounds. |
| Descriptors (primary) |
muscle testing; lead; diseases of peripheral nervous system; exposure; electrodiagnosis; electromyography; nerve stimulation tests |
| Descriptors (secondary) |
experimental determination |
| Document type |
D - Periodical articles |
| Country / State or Province | France |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Diseases of the nervous system
Lead and compounds
|
